nfkb2 | NFKB2 Gene - GeneCards | NFKB2 Protein

Keyword	CPC	PCC	Volume	Score	Length of keyword
nfkb2	1.61	0.8	145	86	5

Keyword	CPC	PCC	Volume	Score
nfkb2	0.56	0.5	2970	100
nfkb2 gene	1.29	0.1	5307	65
nfkb2 antibody	1.56	0.9	388	76
nfkb2 relb	0.42	0.2	8848	92
nfkb2 shrna	0.33	0.5	9485	69
nfkb2 protein	1.14	0.6	440	2
nfkb2 mutation	0.37	0.1	1505	18
nfkb1 gene	1.19	0.5	8714	79
nfkb1 genecards	0.34	0.6	9135	33

Search Results related to nfkb2 on Search Engine

NFKB2 Gene - GeneCards | NFKB2 Protein | NFKB2 Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=NFKB2

WEBApr 3, 2024 · NFKB2 (Nuclear Factor Kappa B Subunit 2) is a Protein Coding gene. Diseases associated with NFKB2 include Immunodeficiency, Common Variable, 10 and Common Variable Immunodeficiency. Among its related pathways are MyD88 dependent cascade initiated on endosome and Cytosolic sensors of pathogen-associated DNA.

DA: 9 PA: 93 MOZ Rank: 58

NFKB2 - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/NFKB2

WEBThe mutation occurs at the C-terminus of NFKB2 and it causes common variable immunodeficienciency which in turn causes endocrine deficiency and immunodeficiencies. A NFKB2 mutation can cause things like adrenocorticotropic hormone deficiency and DAVID syndrome which is a pituitary hormone deficiency and CVID.

DA: 40 PA: 55 MOZ Rank: 23

NFKB2 nuclear factor kappa B subunit 2 [ (human)]
nih.gov

https://www.ncbi.nlm.nih.gov/gene/4791

WEBApr 11, 2024 · NFKB2 inhibits NRG1 transcription to affect nucleus pulposus cell degeneration and in fl ammation in intervertebral disc degeneration. An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-kappaB module.

DA: 28 PA: 2 MOZ Rank: 94

NF-κB subunits direct kinetically distinct transcriptional ... - Nature
nature.com

https://www.nature.com/articles/s41590-023-01561-7

WEBJul 31, 2023 · NF-κB has been shown to be necessary for a subset of human B cell lymphomas 44,45; translocations of REL and NFKB2 have been noted in others 16,46. Target genes that mediate NF-κB’s...

DA: 71 PA: 52 MOZ Rank: 96

Signaling via the NFκB system - PMC - National Center for
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363188/

WEBAnother transcriptional target gene that is induced by nuclear NFκB activity is the nfkb2 gene, which produces the p100 protein. 4 p100 was first known as the precursor for the p52 protein, a dimerization partner of RelB and potentially other Rel proteins.

DA: 35 PA: 24 MOZ Rank: 64

NF-κB: At the Borders of Autoimmunity and Inflammation - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381650/

WEBAug 9, 2021 · NFKB2 and Autoimmunity Autosomal Dominant (AD) NFKB2 /p100/p52 mutations have been identified in patients with common variable immunodeficiency (CVID). These patients exhibit recurrent respiratory infections, hypogammaglobulinemia, alopecia, and adrenal insufficiency.

DA: 81 PA: 39 MOZ Rank: 85

NFKB2 mediates colorectal cancer cell immune escape and …
wiley.com

https://onlinelibrary.wiley.com/doi/10.1002/mco2.521?af=R

WEBApr 24, 2024 · NFKB2 interacts with STAT2, which results in an increase in phosphorylated STAT2 levels and the promotion of PD-L1 expression. Targeting NFKB2 significantly promotes the PD-1 antibody immune checkpoint blockade therapy, with the crucial contribution of CD8 + T-cell infiltration (graphic abstract image).

DA: 84 PA: 100 MOZ Rank: 90

The non-canonical NF-κB pathway in immunity and inflammation
nature.com

https://www.nature.com/articles/nri.2017.52

WEBJun 5, 2017 · The non-canonical NF-κB pathway has been implicated in the pathogenesis of IgA nephropathy, a leading cause of primary glomerulonephritis kidney diseases, which are characterized by...

DA: 79 PA: 34 MOZ Rank: 82

Shaping the nuclear action of NF-κB - Nature
nature.com

https://www.nature.com/articles/nrm1368

WEBMay 1, 2004 · NFKB2, which encodes p100 and p52, and BCL3, which encodes a member of the IκB family, are involved in chromosomal translocations that are found in various forms of chronic lymphocytic...

DA: 32 PA: 56 MOZ Rank: 40

An epithelial Nfkb2 pathway exacerbates intestinal inflammation …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/34155144/

WEBJun 22, 2021 · In sum, the regulation of latent NF-κB dimers appears to link noncanonical Nfkb2 signaling to RelA-driven inflammatory pathologies and may provide for therapeutic targets. Keywords: NF-κB; Nfkb2; inflammatory …

DA: 66 PA: 56 MOZ Rank: 34