replication slippage | Replication Slippage - an overview

Keyword	CPC	PCC	Volume	Score	Length of keyword
replication slippage	0.69	0.1	3583	37	20
replication	1.44	0.2	7853	38	11
slippage	1.77	0.2	1507	52	8

Keyword	CPC	PCC	Volume	Score
replication slippage	1.98	0.4	6038	4
replication slippage definition	1.8	0.2	8428	67
replication slippage diagram	1.86	0.8	2379	93
replication slippage in pcr	0.43	0.3	9972	68
what is replication slippage	1.56	0.9	3844	40
dna replication slippage	1.92	0.1	4457	70
strand slippage during dna replication	0.13	0.7	4608	13

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Replication Slippage - an overview | ScienceDirect Topics
sciencedirect.com

https://www.sciencedirect.com/topics/neuroscience/replication-slippage

WEBReplication slippage is known to cause variation of a few repeat units in microsatellites due to a local misalignment of the template and nascent strands during a brief detachment of the DNA polymerase (Levinson and Gutman, 1987 Schloetterer and Tautz, 1992).

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Errors in DNA Replication | Learn Science at Scitable - Nature
nature.com

https://www.nature.com/scitable/topicpage/dna-replication-and-causes-of-mutation-409/

WEBReplication errors can also involve insertions or deletions of nucleotide bases that occur during a process called strand slippage. Sometimes, a newly synthesized strand loops out a bit,...

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Replication slippage involves DNA polymerase pausing and dissociation
embopress.org

https://www.embopress.org/doi/full/10.1093/emboj/20.10.2587

WEBMay 15, 2001 · We conclude that the polymerase arrested by the hairpin structure dissociates from DNA and is thus trapped by the heparin. This shows that replication slippage involves dissociation of the polymerase upon arrest.

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The mechanism of replication stalling and recovery within ... - Nature
nature.com

https://www.nature.com/articles/s41467-022-31657-x

WEBJul 19, 2022 · The mechanism of replication stalling and recovery within repetitive DNA. Corella S. Casas-Delucchi, Manuel Daza-Martin, Sophie L. Williams & Gideon Coster. Nature Communications 13, Article...

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Replication Slippage - an overview | ScienceDirect Topics
sciencedirect.com

https://www.sciencedirect.com/topics/medicine-and-dentistry/replication-slippage

WEBThe replication slippage model makes two major predictions. First, as DNA replication is linked to the cell cycle, expansion should be a cell-cycle-dependent event. Second, slippage products must escape mismatch repair to become fixed as mutations (see Fig. 35-2 ).

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Microsatellites: simple sequences with complex evolution
nature.com

https://www.nature.com/articles/nrg1348

WEBJun 1, 2004 · The main mechanism of mutation is replication slippage, which results from the transient dissociation of the replicating DNA strands followed by misaligned reassociation. Most primary mutations...

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Frontiers | Replication slippage of the thermophilic DNA …
frontiersin.org

https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2014.00403/full

WEBAug 6, 2014 · Replication slippage or slipped-strand mispairing involves the misalignment of DNA strands during the replication of repeated DNA sequences, and can lead to genetic rearrangements such as microsatellite instability.

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7.1D: Slipped-Strand Mispairing - Biology LibreTexts
libretexts.org

https://bio.libretexts.org/Bookshelves/Microbiology/Microbiology_(Boundless)/07%3A_Microbial_Genetics/7.01%3A_Genes/7.1D%3A_Slipped-Strand_Mispairing

WEBSlipped strand mispairing (SSM) is a process that produces mispairing of short repeat sequences during DNA synthesis. LEARNING OBJECTIVES. Explain how slipped-strand mispairing can be used as a mechanism to regulate gene …

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18.4D: Gene Duplications and Divergence - Biology LibreTexts
libretexts.org

https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Book%3A_General_Biology_(Boundless)/18%3A_Evolution_and_the_Origin_of_Species/18.04%3A_Evolution_of_Genomes/18.4D%3A_Gene_Duplications_and_Divergence

WEBOct 31, 2023 · Replication slippage is an error in DNA replication, which can produce duplications of short genetic sequences. During replication, DNA polymerase begins to copy the DNA, and at some point during the replication process, the polymerase dissociates from the DNA and replication stalls.

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Relatively semi-conservative replication and a folded slippage …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430839/

WEBThe folded replication slippage model provides a reasonable explanation for the continuous occurrences of simple sequence repeats in genomes. This model also contributes to the explanation of STR-to-genome evolution and is an alternative model that complements semi-conservative replication.

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