Keyword Analysis & Research: pirna


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  • Piwi-interacting RNA - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/Piwi-interacting_RNA

    WebPiwi-interacting RNA ( piRNA) is the largest class of small non-coding RNA molecules expressed in animal cells. [1] [2] [3] piRNAs form RNA- protein complexes through interactions with piwi -subfamily Argonaute proteins. These piRNA complexes are mostly involved in the epigenetic and post-transcriptional silencing of transposable elements and ...

    DA: 13 PA: 88 MOZ Rank: 100

  • Pirna - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/Pirna

    WebPirna (German: ⓘ; Upper Sorbian: Pěrno, pronounced [ˈpʲɪʁnɔ]) is a town in Saxony, Germany and capital of the administrative district Sächsische Schweiz-Osterzgebirge. The town's population is over 37,000. Pirna is located near Dresden and is an important district town as well as a Große Kreisstadt.

    DA: 69 PA: 78 MOZ Rank: 41

  • PIWI-interacting RNAs: small RNAs with big functions

    nature.com

    https://www.nature.com/articles/s41576-018-0073-3

    WebNov 16, 2018 · Here, we discuss how a common piRNA pathway allows animals to recognize diverse targets, ranging from selfish genetic elements to genes essential for gametogenesis.

    DA: 64 PA: 88 MOZ Rank: 18

  • Emerging roles and functional mechanisms of PIWI-interacting …

    nature.com

    https://www.nature.com/articles/s41580-022-00528-0

    WebSep 14, 2022 · EMBO Reports (2024) PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with proteins of the PIWI clade of the Argonaute family. First identified in animal germ...

    DA: 70 PA: 21 MOZ Rank: 26

  • The birth of piRNAs: how mammalian piRNAs are produced, …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114089/

    WebNov 1, 2021 · They play critical roles in a range of functions, including transposable element suppression, gene expression regulation, imprinting, and viral defense. In mammals, piRNAs are the most abundant small RNAs in adult testes and the only small RNAs that direct epigenetic modification of chromatin in the nucleus.

    DA: 50 PA: 5 MOZ Rank: 37

  • Defining the functions of PIWI-interacting RNAs - Nature

    nature.com

    https://www.nature.com/articles/s41580-021-00336-y

    WebJan 22, 2021 · PIWI-interacting RNAs (piRNAs) have a central role in animal gametogenesis and fertility, silencing transposons, fighting viruses and regulating endogenous genes 1. Although the proteins...

    DA: 30 PA: 47 MOZ Rank: 25

  • PIWI-Interacting RNAs (piRNAs): Promising Applications as …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829394/

    WebJan 27, 2022 · PIWI-interacting RNAs (piRNAs) are the least studied sncRNAs and participate in epigenetic and retrotransposon post-transcriptional gene silencing by interacting with PIWI proteins (Xiao and Ke, 2016; Ozata et al., 2019). piRNAs were first identified in germ cell lines and their expression was also confirmed in somatic tissues …

    DA: 41 PA: 55 MOZ Rank: 92

  • PIWI-Interacting RNA: Its Biogenesis and Functions - PubMed

    nih.gov

    https://pubmed.ncbi.nlm.nih.gov/25747396/

    WebPIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24-31 nucleotides in length. They associate with PIWI proteins, which constitute a germline-specific subclade of the Argonaute family, to form effector complexes known as piRNA-induced silencing complexes, which repress transposons vi ….

    DA: 84 PA: 48 MOZ Rank: 39

  • The Biogenesis and Functions of piRNAs in Human Diseases

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283962/

    WebSep 4, 2020 · Mounting studies have revealed that the dysregulation of piRNAs may cause epigenetic changes and contribute to diverse diseases. This review illustrates piRNA biogenesis, mechanisms behind piRNA-mediated gene regulation, and changes of piRNAs in different diseases, especially in cancers.

    DA: 18 PA: 89 MOZ Rank: 81

  • PIWI-interacting RNAs: small RNAs with big functions - PubMed

    nih.gov

    https://pubmed.ncbi.nlm.nih.gov/30446728/

    WebAbstract. In animals, PIWI-interacting RNAs (piRNAs) of 21-35 nucleotides in length silence transposable elements, regulate gene expression and fight viral infection. piRNAs guide PIWI proteins to cleave target RNA, promote heterochromatin assembly and methylate DNA.

    DA: 42 PA: 45 MOZ Rank: 1