Keyword Analysis & Research: centromere


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  • Centromere - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/Centromere

    WEBThe physical role of the centromere is to act as the site of assembly of the kinetochores – a highly complex multiprotein structure that is responsible for the actual events of chromosome segregation – i.e. binding microtubules and signaling to the cell cycle machinery when all chromosomes have adopted correct attachments to the spindle, so that...

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  • Centromere - Definition, Function and Types | Biology Dictionary

    biologydictionary.net

    https://biologydictionary.net/centromere/

    WEBApr 28, 2017 · Centromere Definition. The centromere is the point on a chromosome where mitotic spindle fibers attach to pull sister chromatids apart during cell division. When a cell seeks to reproduce itself, it must first make a complete copy of each of its chromosomes, to ensure that their daughter cell receives a full complement of the parent cell’s DNA.

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  • The molecular basis for centromere identity and function

    nature.com

    https://www.nature.com/articles/nrm.2015.5

    WEBNov 25, 2015 · Abstract. The centromere is the region of the chromosome that directs its segregation in mitosis and meiosis. Although the functional importance of the centromere has been appreciated for more...

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  • Centromere - National Human Genome Research Institute

    genome.gov

    https://www.genome.gov/genetics-glossary/Centromere

    WEB5 days ago · Centromere. updated: April 19, 2024. Definition. 00:00. … The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.

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  • Centromere | chromosome, DNA, replication | Britannica

    britannica.com

    https://www.britannica.com/science/centromere

    WEBcentromere, structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored.

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  • The variation and evolution of complete human centromeres

    nature.com

    https://www.nature.com/articles/s41586-024-07278-3

    WEBApr 3, 2024 · Complete assembly of centromeres from two hydatidiform moles, CHM1 and CHM13, reveals both small- and large-scale variation in centromere sequence, structure and epigenetic landscape. The CHM1...

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  • Chromosome Segregation in Mitosis: The Role of Centromeres

    nature.com

    https://www.nature.com/scitable/topicpage/chromosome-segregation-in-mitosis-the-role-of-242/

    WEBFigure Detail. After nearly two decades of genetic and biochemical analyses, scientists now know that each centromere is a region of highly specialized chromatin.

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  • Centromeres: From chromosome biology to biotechnology …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616519/

    WEBJul 7, 2022 · Centromeres are the specialized chromosomal regions that are required for the maintenance of genomic stability during cell divisions, and their inheritance and function are strictly dependent on genetic and epigenetic components in most species.

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  • Centromere Structure and Function - PMC - National Center for

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535225/

    WEBAbstract. The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase.

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  • Complete genomic and epigenetic maps of human centromeres

    science.org

    https://www.science.org/doi/10.1126/science.abl4178

    WEBStudying centromere positioning across many samples, across families, and across different tissues from the same individuals will reveal the extent of this epigenetic plasticity in centromere localization and how this epigenetic variation …

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