PDB-101: Learn: Exploring the Structural Biology of Cancer
https://pdb101.rcsb.org/learn/exploring-the-structural-biology-of-cancer
WEBIn normal cells, Ras relays signals from receptors embedded in the outer membrane to many intracellular proteins contributing to cellular structure and growth. In many cancer cells, the Ras oncogene encodes a variant of the protein, such as the G12C variant shown here, that is continually active, promoting growth without the need for activation ...
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