Keyword Analysis & Research: 53bp1


Keyword Analysis

Keyword CPC PCC Volume Score Length of keyword
53bp11.830.13907575

Keyword Research: People who searched 53bp1 also searched

Keyword CPC PCC Volume Score
53bp11.920.7555168
53bp1 foci1.320.5966120
53bp1 antibody1.721493188
53bp1 h2ax0.330.8393587
53bp1 nhej1.490.3328464
53bp1 gene1.041269831
53bp1 atm1.330.855280
53bp1 domain1.210.8594423
53bp1 p531.490.4397330
53bp1 dna damage0.40.1152646
53bp1 structure1.350.7521758

Search Results related to 53bp1 on Search Engine

  • TP53BP1 - Wikipedia

    wikipedia.org

    https://en.wikipedia.org/wiki/TP53BP1

    WEB1GZH, 1KZY, 1XNI, 2G3R, 2IG0, 2LVM, 2MWO, 2MWP, 3LGF, 3LGL, 3LH0, 4CRI, 4RG2, 4X34, 5ECG. Identifiers. Aliases. TP53BP1, 53BP1, p202, p53BP1, TP53, TDRD30, tumor protein p53 binding protein 1. External IDs. OMIM: 605230 MGI: 1351320 HomoloGene: 4137 GeneCards: TP53BP1. Gene location ( Human) Chr.

    DA: 69 PA: 19 MOZ Rank: 90

  • Double-strand break repair: 53BP1 comes into focus - Nature

    nature.com

    https://www.nature.com/articles/nrm3719

    WEBDec 11, 2013 · 53BP1 is a key regulator of DSB repair pathway choice. During G1, it promotes non-homologous end-joining (NHEJ)-mediated DSB repair by antagonizing long-range DNA end-resection, which is...

    DA: 41 PA: 46 MOZ Rank: 12

  • 53BP1: A key player of DNA damage response with critical ... - PubMed

    nih.gov

    https://pubmed.ncbi.nlm.nih.gov/30497961/

    WEBThe tumor suppressor P53-binding protein 1 (53BP1), as one of the main mediators of DDR, plays a pivotal role in orchestrating the choice of double-strand break (DSB) repair pathway and contains interaction surfaces for numerous DSB-responsive proteins.

    DA: 24 PA: 87 MOZ Rank: 59

  • 53BP1 is a reader of the DNA-damage-induced H2A Lys 15

    nature.com

    https://www.nature.com/articles/nature12318

    WEBJun 12, 2013 · 53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by non-homologous end joining. To accomplish its...

    DA: 81 PA: 59 MOZ Rank: 23

  • 53BP1: Keeping It under Control, Even at a Distance from DNA …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778356/

    WEBDec 16, 2022 · The P53-binding protein 1 (53BP1) plays a pivotal role in the choice of DSB repair mechanism, promotes checkpoint activation and preserves genome stability upon DSBs. By preventing DSB end resection, 53BP1 promotes NHEJ over HR.

    DA: 24 PA: 28 MOZ Rank: 81

  • Understanding the actions of 53BP1 - Nature

    nature.com

    https://www.nature.com/articles/nrm.2016.120

    WEBSep 1, 2016 · The role of p53-binding protein 1 (53BP1) — a p53-interacting protein — in DNA repair is well defined, although it is less clear how it influences p53 biology. Now, Cuella-Martin et al....

    DA: 51 PA: 12 MOZ Rank: 100

  • A role of the 53BP1 protein in genome protection: structural and

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519998/

    WEBApr 4, 2019 · It is generally accepted that 53BP1 mediates the NHEJ mechanism, while HDR is activated via a BRCA1-dependent signaling pathway. Interestingly, the 53BP1 protein appears relatively quickly at DSB sites, while BRCA1 is functional at later stages of DNA repair, as soon as the Mre11-Rad50-Nbs1 complex is recruited to the DNA lesions.

    DA: 16 PA: 62 MOZ Rank: 14

  • 53BP1: Pro Choice in DNA Repair - PMC - National Center for

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946699/

    WEBRecent work has revealed that 53BP1 controls 5′ end resection at DNA ends, mediates synapsis of DNA ends, promotes the mobility of damaged chromatin, improves DSB repair in heterochromatic regions, and contributes to lethal mis-repair of DSBs in …

    DA: 15 PA: 17 MOZ Rank: 48

  • 53BP1 contributes to regulation of autophagic clearance of

    nature.com

    https://www.nature.com/articles/srep45290

    WEBMar 27, 2017 · Here we provide evidence that 53BP1, a DNA damage response protein, is involved in regulating mitochondrial clearance from the cell via a type of autophagy termed mitophagy.

    DA: 58 PA: 47 MOZ Rank: 100

  • 53BP1, a Mediator of the DNA Damage Checkpoint | Science

    science.org

    https://www.science.org/doi/10.1126/science.1076182

    WEBOct 3, 2002 · 53BP1 was identified through its ability to bind to the tumor suppressor protein p53 through 53BP1's COOH-terminal BRCT (Brca1 carboxyl-terminus) repeats ( 1, 2 ), which are found in many DNA damage response proteins (3–8). 53BP1 responds to DNA double-strand breaks (9–12), quickly relocalizing to discrete nuclear foci upon exposure …

    DA: 55 PA: 32 MOZ Rank: 45